Did I know that the Duesberg paper would be controversial?Charlton's farewell lists a few of the times where controversial papers published in Med Hypotheses have gone on to prove highly influential.
Yes. I knew that Duesberg was being kept out of the mainstream scientific literature, and that breaching this conspiracy would annoy those who had succeeded in excluding him for so long.
When I published the Duesberg article, I envisaged it meeting one of two possible fates.
In the first scenario, the paper would be shunned or simply ignored - dropped down the memory hole. This is what has usually happened in the past when a famous scientist published ideas that their colleagues regarded as misguided or crazy. Linus Pauling (1901-94) was a Nobel prizewinner and one of the most important chemists in history. Yet his views on the medical benefits of vitamin C were regarded as wrong. He was allowed to publish them, but (rightly or wrongly) they were generally ignored in mainstream science.
In the other scenario, Duesberg's paper would attract robust criticism and (apparent) refutation. This happened with Fred Hoyle (1915-2001), a Fellow of the Royal Society whose work on the "steady state" theory of the Universe made him one of the most important cosmologists of the late 20th century. But his views on the origins of life on Earth and the Archaeopteryx fossil were generally regarded as eccentric. Hoyle's ideas were published, attracted much criticism, and were (probably) refuted.
So I expected that Duesberg's paper either would be ignored or would trigger letters and other papers countering the ideas and evidence presented. Medical Hypotheses would have published these counter-arguments, then provided space for Duesberg to respond to the criticisms and later allowed critics to reply to Duesberg's defence. That is, after all, how real science is supposed to work.
What I did not expect was that editors and scientists would be bypassed altogether, and that the matter would be settled by the senior managers of a multinational publishing corporation in consultation with pressure-group activists. Certainly, that would never have happened 25 years ago, when I began research in science.
It's a real shame that diversity across journals can't be maintained. Medical Hypotheses is one of the very few journals that is editorially reviewed rather than peer reviewed. It would be a mistake if the majority of journals were run this way, but it's rather important that a few out there are, provided the editor has a suitably contrarian turn.
Let's hope that Charlton eventually begins a new journal to take its place.