Lakhani et al used ACS and health insurance data (724,513 sibling pairs; 56,396 twin pairs) to tease out the relative contributions of heritable factors, shared environment, and socioeconomic status across a whole pile of disorders; it's in Nature: Genetics.
Here's a decent write-up.
Here's what things look like for morbid obesity. h2 (green bar) is genetics. c2 (peach bar) is shared environment, adjusting for SES factors. SES (small purple bar) is SES.
Previously:
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